Cleanrooms & Containment Environments
Biobubble Softwall Cleanrooms And Containment Enclosures Offer The Most Flexibility For Adaptable, Cost-effective Solutions.


Modular, flexible class 10,000 ISO 7, Class 1,000 ISO 6, Class 100 ISO 5 Cleanrooms
- Manufacturing
- Life Sciences
- Vivariums
- Biomedical Research
- Pharmaceutical
Primary and Secondary Containment for Biosafety Levels BSL-2, BSL-3, BSL-4, ABSL-2, ABSL-3, ABSL-4, USDA BSL-3-Ag
- COVID-19/Coronavirus
- Cell Sorters, Liquid Handling robots and Other Laboratory Instruments
- Infectious Diseases, Including Ebola, Anthrax, SARS and H1N1
- Quarantine Environments
- Pharmaceutical Research
- Food Safety Research
- Vivariums, Biocontainment Facilities, Research Facilities
- Increase Flexibility
- Achieve a Higher Level of Cleanliness or Containment
- 30-60% Cost Savings Over Hard Construction
The bioBUBBLE Benchtop Biocontainment Enclosure (BBE) is an ideal containment solution for cell sorters, cell analyzers, incubators, centrifuges, microscopes, or any benchtop laboratory equipment used in BSL-2 and BSL-3 applications. The BBE captures and contains aerosols and other airborne particulates emitted during laboratory procedures to protect workers and the lab environment.
Watch: bioBubble in the Lab
Catch a glimpse of a bioBubble enclosure in the ancient biomolecular lab at 6:13.
Chuck Spengler, founder of bioBUBBLE, is part Cherokee and actively participates in several programs dedicated to restoring Mother Earth.
Why Choose bioBUBBLE?
Custom Solutions – Tailored to fit your automated system and workspace with options for size and access points leaving no wasted space.
Easy Access – to all sides of the equipment for maintenance and calibration.
Controlled Airflow & Filtration – HEPA-filtered, positive pressure enclosures protect the product, negative pressure environments protect personnel and the environment.
Durable, Lightweight Construction – Built with high-strength aluminum frames and clear panels for visibility and structural integrity.
Soft Walls – reduce vibration and minimize noise
Easy Installation & Mobility – Modular setup allows for simple assembly and relocation as your needs evolve.
Whether you want to improve data quality or provide safety, integrating a bioBUBBLE enclosure improves your process.
Where bioBUBBLE Works:
- Research & Development Labs
- Pharmaceutical Companies
- Universities & Innovation Centers
From research incubator labs to large pharmaceutical companies, we have an enclosure that will work for you.
Dr. Gary L. Keller
Director, Veterinary Services
Children’s Hospital Research Foundation
“I have been using the bioBUBBLE equipment and working with the staff for over 25 years. The staff is dedicated, cooperative, responsive and they are delightful individuals. The equipment works exceedingly well, keeps the environment super clean and is very dependable. The company is very flexible and will design exactly what you need. I would, without reservation, highly recommend them to anyone in the laboratory animal community.”
Dr. Robert P. Ellis, PhD, CBSP, DACVM
Director of Biosafety
Colorado State University
“We have used bioBUBBLE for over 25 years for many customized containment applications. The sizes of the containment and the containment applications have ranged from an isolation unit in a greenhouse (in order to contain potential pollen) to containment of animals exposed to Risk Group 3 infectious agents. The bioBUBBLE staff have all been very helpful in design and installation of their product. The bioBUBBLE custom product is usually much more economically priced than comparable containment products. I have very high regard for the product and the professional service of bioBUBBLE.”
Projects
Institut Clinique de la Souris
Upgrading Health Status in an SPF Facility Without Renovation or Downtime
University of Calgary
Rederivation Facility: Ultra-Clean and Containment Solution
Texas A&M University
BSL 2 Food Safety Research Facility within a Leased Space
Lawrence Berkeley National Laboratories
Ultra-Clean University Research Vivarium
Kansas State University
Customized Primary Containment Environment for Foodborne Pathogens
Australian BioResources
Breeding and Research Facility for over 400 Mouse Strains