Upgrading Health Status in an SPF Facility Without Renovation or Downtime

Institut Clinique de la Souris | Illkirch, France


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Challenge:

Improve mouse health and generate mice free of Helicobacter, Pasturella, and Norovirus in a fully occupied, endemically infected breeding facility.

Solution:

Install a Class 100/ ISO 5 cleanroom for rederivation and housing of GEM strains.

Results:

After 10 weeks in the clean environment, rederived mice are free from Norovirus, Helicobacter and Pasteurella. Accomplished without any downtime or building renovations.